China (Mainland)
SGC707 CAS NO.1687736-54-4
- Min.Order: 1 Gram
- Payment Terms: T/T,Other
- Product Details
Keywords
- 1687736-54-4
- SGC707
- C16H18N4O2
Quick Details
- ProName: SGC707
- CasNo: 1687736-54-4
- Molecular Formula: C16H18N4O2
- Appearance: solid powder
- Application: For research only.
- DeliveryTime: Within 3 days after payment
- PackAge: as required
- Port: Beijing or Guangzhou
- ProductionCapacity: 100 Gram/Month
- Purity: 98%
- Storage: Dry, dark and at 0 - 4 C for short ter...
- Transportation: Shipped under ambient temperature as n...
- LimitNum: 1 Gram
Superiority
SGC707, purity > 98%, is in not stock. This is our mature product with high quality and competitive price. Welcome to order it as well as customized it. Also, we would like to develop strategic partnership with our clients.
Note: We only provide quotation to customers who disclose their organization detail. We must know who will use the product since we do not sell products for human and household use. Inquiries without enough detail contact information will be ignored. Quotation of custom synthesis is only provided through email, will not be provided through phone.
Details
CAS No.：1687736-54-4
LAL ID：xqy-170112
Chemical Names: SGC707; 1687736-54-4.
Molecular Formula: C16H18N4O2
Molecular Weight: 298.346 g/mol
Purity: 98%
The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%.
Description: SGC707 is a potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase?3 (PRMT3). SGC707 is a potent PRMT3 inhibitor (IC50 =31±2?nM, KD =53±2?nM) with outstanding selectivity (selective against 31 other methyltransferases and more than 250 non-epigenetic targets). The mechanism of action studies and crystal structure of the PRMT3-SGC707 complex confirm the allosteric inhibition mode. Importantly, SGC707 engages PRMT3 and potently inhibits its methyltransferase activity in cells. It is also bioavailable and suitable for animal studies. This well-characterized chemical probe is an excellent tool to further study the role of PRMT3 in health and disease.