China (Mainland)
BMS-833923 CAS NO.1059734-66-5
- Min.Order: 1 Gram
- Payment Terms: T/T,
- Product Details
Keywords
- BMS-833923
- 1059734-66-5
- manufacturer
Quick Details
- ProName: BMS-833923
- CasNo: 1059734-66-5
- Molecular Formula: C30H27N5O
- Appearance: white solid powder
- Application: For research only.
- DeliveryTime: 1-3 days
- Port: Beijing or Guangzhou
- ProductionCapacity: 100 Gram/Month
- Purity: >98% (or refer to the Certificate of A...
- Storage: Dry, dark and at 0 - 4 C for short ter...
- Transportation: Shipped under ambient temperature as n...
- LimitNum: 1 Gram
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Details
CAS No.：1059734-66-5
LAL ID：xqy-170103
Chemical Names: BMS-833923; 1059734-66-5
Molecular Formula: C30H27N5O
Molecular Weight: 473.58 g/mol
Purity: 98%
Description:
Oral, small molecule antagonist of the Hedgehog (Hh) signaling component Smoothened (SMO). Treatment with BMS 833923 leads to a decreased expression of GLI1 and PTCH1 in EGI-1 cells, reduced tumor growth in vitro, and a prolongation of survival in vivo in different human cancers. Additionally, SMO inhibition by BMS 833923 leads to decreased proliferation and induces apoptosis in esophageal adenocarcinoma cells (EACs).